Continuous Buffer Management System
We build this solution as an alternative to the traditional buffer tank farm. The economical benefits are significant both capital- and operation-wise. Our solution is based on inline mixing and multi-relay tank system that allow the buffer consumption clients to use the buffer as if it were traditional tank farm. We made it a robust system by standardizing on system design and process control. Our innovative batch approach and continuous buffer filling strategy made the solution a viable alternative to traditional tank farm. Our team have the engineering capability to design and build the system to fit to your new or existing plant. Our experts bring in decades of experience of high end pharmaceutical hardware and flow system design, and process control solution design using DCS platform and S88 batch management standard. Our project execution follows a GAMP framework from Lisure Quality System to meet our pharmaceutical customers' need for process validation.
Customized Design
Computer Deployment
Online Monitoring
Precise Feedback
Stable Control System
Simple & High Efficiency
The system is aligned according to the customer's plant layout, process train, and specific buffer type/ amount required. CBMS has been installed for production scale above 100,000 L
Computer calculates the components such as concentrates and WFI required to prepare the buffer according to pre-set formulas in the batch recipe.
Preparation of concentrate solutions is usually simple as most of them are designed as single-component solution.
Real-time inline monitoring of buffer preparation process ensures only qualified buffer goes into production process, with complete data logging capability.
Buffer preparation is based on patented flow control strategy with accurate massflow/ PH/ conductivity feedback with no requirement for manual sampling.
Valve proximity feedback, real-time monitoring of equipment status ensures production safety and stability.
Highly reliable industrial control platform (DeltaV), batch recipe complying with ISA88 batch operation standard, ensures the system can be easily integrated into plant DCS or MES.
