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High-packing columns

Multi-column Chromatography System is used in the scale-up production of high-packing column chromatography, solving the problem that a single chromatography column cannot be packed more than 50cm. The multi-column chromatography system can be connected to multiple chromatography columns, each column packed 40cm before use in series. Parallel connection during equilibrium, cleaning and regeneration, and series connection during sample loading and elution, reducing the overall time by more than 40%. The alternation between parallel and series operation of the column segments is what leads to the gain in savings and overall throughput/efficiency.

  • The system is designed to drastically reduce pre-elution and post-elution processing times for gel filtration chromatography media.

  • The system is designed to provide robust process control during this critical downstream step.

  • Use up to 3 columns of production specifications, control function through the system, each column can be switched in the steps of loading/ elution/ washing/ regeneration at the same time.

  • It supports multiple chromatographic columns to load samples in series, which greatly increases the sample load of the chromatographic packing and improves the utilization efficiency of the packing.

  • Human-machine interface (HMI) commands to record key process parameters.

  • The program of the system software realizes the continuity of the sample loading step through the automatic program control, such as the UV value target.